Author

G. Mardones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1

Frequent Co-Authors

K. Zavala· 3 shared F. Morera· 2 shared J. Opazo· 2 shared L. Vargas-Chacoff· 2 shared P. Burgos· 2 shared A. Gonzalez· 1 shared A. Rojas· 1 shared A. Soza· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersEvolutionary Biology

K. Zavala

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Reelin Receptor ApoER2 is a Cargo for the Adaptor Protein Complex AP-4: Implications for Hereditary Spastic Paraplegia.

M. Caracci, H. Pizarro, C. Alarcon-Godoy, L. M. Fuentealba, P. Farfan, R. De Pace, N. Santibanez, V. A. Cavieres, T. Pastor, J. Bonifacino, G. Mardones, M.-P. Marzolo

This study identifies ApoER2 as a cargo of the AP-4 complex and shows that AP-4 defects affect its trafficking and Reelin signaling, potentially contributing to Hereditary Spastic Paraplegia.

bioRxiv · Dec 21, 2023Cell Biology

Evolution of ion channels in cetaceans: A natural experiment in the tree of life

C. Uribe, M. Nery, K. Zavala, G. Mardones, G. Riadi, J. Opazo

This study examines ion channel evolution in cetaceans, finding fewer genes and more annotated channels, positive selection in key channels, and a higher gene turnover rate compared to non-cetacean mammals.

bioRxiv · Jun 15, 2023Evolutionary Biology

Identification of multiple TAR DNA Binding Protein retropseudogene lineages during the evolution of primates

J. Opazo, K. Zavala, L. Vargas-Chacoff, F. Morera, G. Mardones

This study identifies multiple TAR DNA Binding Protein retropseudogene lineages in primate evolution, highlighting their potential regulatory roles despite lacking protein-coding function.

bioRxiv · May 24, 2021Evolutionary Biology

How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member

J. C. Opazo, M. Vandewege, F. G. Hoffmann, K. Zavala, C. Melendez, C. Luchsinger, V. Cavieres, L. Vargas-Chacoff, F. Morera, P. Burgos, C. Tapia-Rojas, G. Mardones

The paper investigates the evolutionary history of sirtuin genes in vertebrates, identifying a new family member and showing at least eight paralogs traceable to a common ancestor.

bioRxiv · Jul 17, 2020Evolutionary Biology

The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport

H. Bustamante, K. Cereceda, A. Gonzalez, G. Valenzuela, Y. Cheuquemilla, S. Hernandez, E. Arias, C. Cerda-Troncoso, S. Bandau, A. Soza, G. Kausel, B. Kerr, G. Mardones, J. Cancino, R. Hay, , P. Burgos

The paper identifies PSMD14 as a regulator of Golgi-to-ER retrograde transport and macroautophagy through its role in K63-Ub chain deubiquitination.

bioRxiv · Jan 29, 2020Cell Biology