Author

V. A. Cavieres

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

C. Cerda-Troncoso· 2 shared M. Varas-Godoy· 2 shared P. V. Burgos· 2 shared A. Caceres-Verschae· 1 shared A. E. Gonzalez· 1 shared A. Rojas-Fernandez· 1 shared B. Gaete-Ramirez· 1 shared C. Alarcon-Godoy· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

C. Cerda-Troncoso

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Reelin Receptor ApoER2 is a Cargo for the Adaptor Protein Complex AP-4: Implications for Hereditary Spastic Paraplegia.

M. Caracci, H. Pizarro, C. Alarcon-Godoy, L. M. Fuentealba, P. Farfan, R. De Pace, N. Santibanez, V. A. Cavieres, T. Pastor, J. Bonifacino, G. Mardones, M.-P. Marzolo

This study identifies ApoER2 as a cargo of the AP-4 complex and shows that AP-4 defects affect its trafficking and Reelin signaling, potentially contributing to Hereditary Spastic Paraplegia.

bioRxiv · Dec 21, 2023Cell Biology

Chemo-sEVs release in cisplatin-resistance ovarian cancer cells are regulated by the lysosomal function

C. Cerda-Troncoso, F. Grünenwald, E. Arias-Munoz, V. A. Cavieres, A. Caceres-Verschae, S. Hernandez, B. Gaete-Ramirez, F. Alvarez-Astudillo, R. A. Acuna, M. Ostrowski, P. V. Burgos, M. Varas-Godoy

This study shows that cisplatin-resistant ovarian cancer cells release chemo-sEVs regulated by lysosomal function, with RAB27A silencing restoring lysosomal function and reducing sEVs secretion.

bioRxiv · Feb 3, 2023 · PreprintCancer Biology

Negative modulation of macroautophagy by HERPUD1 is counteracted by an increased ER-lysosomal network with impact in drug-induced stress cell survival

G. Vargas, O. H. Cortes, E. N. Arias-Munoz, S. F. Hernandez-Galaz, C. Cerda-Troncoso, L. Hernandez-Torres, A. E. Gonzalez, M. Tatham, H. A. Bustamante, C. E. Retamal, J. Cancino, M. Varas-Godoy, R. T. Hay, A. Rojas-Fernandez, V. A. Cavieres, P. V. Burgos

The paper identifies HERPUD1 as a negative regulator of macroautophagy, showing that its stabilization promotes ER-lysosomal network expansion and enhances cell survival under stress.

bioRxiv · Jun 14, 2021 · PreprintCell Biology