Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment
S. K. Malladi, R. Singh, S. Pandey, S. Gayathri, K. Kanjo, S. Ahmed, M. S. Khan, P. Kalita, N. Girish, A. Upadhyaya, P. Reddy, I. Pramanick, M. Bhasin, S. Mani, S. Bhattacharyya, , R. Varadarajan
This paper designs a thermotolerant, immunogenic SARS-CoV-2 RBD protein fragment that is stable at high temperatures and elicits neutralizing antibodies in guinea pigs.
bioRxiv · Aug 15, 2020Biophysics