Author

G. P. McVicker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Sen· 2 shared A. E. Clark· 1 shared B. C. Prager· 1 shared B. Li· 1 shared B. Ren· 1 shared D. Park· 1 shared J. A. Bernatchez· 1 shared J. Elster· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Sen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Allele-specific expression links diverse cis-regulatory mutations to recurrent gene dysregulation in high-risk neuroblastoma

A. Sen, Y. Huo, J. Elster, P. E. Zage, G. P. McVicker

The paper uses allele-specific expression analysis in neuroblastoma tumors to identify genes dysregulated by cis-regulatory mutations and copy number alterations.

bioRxiv · Jul 8, 2021 · PreprintCancer Biology

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma.

A. Sen, B. C. Prager, D. Park, Z. Zhu, R. C. Gimple, J. A. Bernatchez, S. Beck, A. E. Clark, J. L. Siqueira-Neto, J. N. Rich, G. P. McVicker

This study identifies genes with allele-specific expression in glioblastoma stem cells, finding SLFN11 loss linked to drug resistance and susceptibility to Zika virus.

bioRxiv · Jun 22, 2021Cancer Biology

Discovery and Functional Characterization of Pro-growth Enhancers in Human Cancer Cells

P. Chen, P. Fiaux, B. Li, K. Zhang, N. Kubo, S. Jiang, R. Hu, S. Wu, M. Wang, W. Wang, G. P. McVicker, P. Mischel, B. Ren

The paper identifies and characterizes pro-growth enhancers in cancer cells using CRISPR screens, finding lineage-specific enhancers associated with poor prognosis and potential therapeutic targets.

bioRxiv · Feb 4, 2021 · PreprintCancer Biology