Author

G. Sriram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. V. Raghuram· 2 shared I. Mittra· 2 shared K. Pal· 2 shared S. Shinde· 2 shared V. Jadhav· 2 shared A. Khan· 1 shared A. Pilankar· 1 shared A. Quinn· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

G. V. Raghuram

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell-free chromatin particles activate immune checkpoints in human T cells: Implications for cancer therapy

S. Shabrish, K. Pal, N. K. Khare, D. Satsangi, A. Pilankar, V. Jadhav, S. Shinde, N. Raphael, G. Sriram, R. Lopes, G. V. Raghuram, H. Tandel, I. Mittra

The paper shows that cell-free chromatin particles activate multiple immune checkpoints in human T cells, suggesting a new approach for cancer immunotherapy.

bioRxiv · Jun 9, 2023 · PreprintImmunology

Therapeutic interventions on human xenografts promote systemic dissemination of oncogenes

G. V. Raghuram, K. Pal, G. Sriram, A. Khan, R. Joshi, V. Jadhav, S. Shinde, A. Sheikh, B. Rane, H. Kangne, I. Mittra

The paper shows that therapeutic interventions in human xenografts increase oncogene dissemination, which can be reduced by chromatin deactivating agents.

bioRxiv · Apr 6, 2023 · PreprintCancer Biology

Bacterially produced small molecules stimulate diatom growth

J. Sittmann, M. Bae, E. Mevers, M. Li, A. Quinn, G. Sriram, J. Clardy, Z. Liu

Two diketopiperazines (DKPs) produced by sporulating Bacillus thuringiensis stimulate diatom P. tricornutum growth and increase lipid content.

bioRxiv · Nov 2, 2020 · PreprintPlant Biology

The Injury Response to DNA Damage Promotes Anti-Tumor Immunity

G. Sriram, L. E. Milling, J.-K. Chen, W. Abraham, E. D. Handly, D. J. Irvine, M. B. Yaffe

This study shows that ex vivo DNA-damaged tumor cells as an adjuvant enhance anti-tumor immunity when combined with immune checkpoint inhibitors, requiring live injured cells and specific signaling pathways.

bioRxiv · Apr 26, 2020 · PreprintCancer Biology