Author

G. T. Hess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

M. C. Bassik· 3 shared C. Ritchie· 2 shared L. Li· 2 shared A. F. Cordova· 1 shared D. H. Siepe· 1 shared J. A. Carozza· 1 shared K. C. Garcia· 1 shared K. Zinn· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

M. C. Bassik

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.

D. H. Siepe, L. T. Henneberg, S. C. Wilson, G. T. Hess, M. C. Bassik, K. Zinn, K. C. Garcia

The paper develops a CRISPRa-based screening platform to identify orphan ligand-receptor interactions by screening secreted proteins against cell surface receptor libraries.

bioRxiv · Jun 22, 2022Cell Biology

The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

L. J. Lahey, X. Wen, R. E. Mardjuki, V. Böhnert, G. T. Hess, C. Ritchie, J. A. Carozza, M. Maduke, M. C. Bassik, L. Li

The paper identifies LRRC8A:C as a cGAMP transporter in human vasculature cells and shows it mediates cGAMP import/export and is the dominant importer in these cells.

bioRxiv · Feb 13, 2020 · PreprintBiochemistry

SLC19A1 is an importer of the immunotransmitter cGAMP

A. F. Cordova, C. Ritchie, G. T. Hess, M. C. Bassik, L. Li

The paper identifies SLC19A1 as the importer of cGAMP and other CDNs, revealing its role in activating the STING pathway and informing CDN-based cancer therapy development.

bioRxiv · Feb 3, 2019Biochemistry