Author

R. E. Mardjuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. A. Carozza· 2 shared L. Li· 2 shared A. L. Markhard· 1 shared C. B. Ramirez· 1 shared C. J. Chou· 1 shared C. Jang· 1 shared C. Ritchie· 1 shared D. Fernandez· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

J. A. Carozza

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Author profile →

3 papers

Recent·Most cited

A PTER-dependent pathway of taurine metabolism linked to energy balance

W. Wei, X. Lyu, A. L. Markhard, S. Fu, R. E. Mardjuki, P. E. Cavanagh, X. Zeng, J. Rajniak, N. Lu, S. Xiao, M. Zhao, M. Dolores Moya-Garzon, S. D. Truong, C. J. Chou, L. W. Wat, , J. Z. Long

This study identifies PTER as the taurine N-acetyltransferase/hydrolase, showing its role in regulating N-acetyltaurine levels and linking it to energy balance and metabolic phenotypes.

bioRxiv · Mar 21, 2024 · PreprintBiochemistry

Structure-aided development of small molecule inhibitors of ENPP1, the extracellular phosphodiesterase of the immunotransmitter cGAMP

J. A. Carozza, J. A. Brown, V. Boehnert, D. Fernandez, Y. AlSaif, R. E. Mardjuki, M. Smith, L. Li

This study develops small molecule ENPP1 inhibitors with sub-nanomolar potency and demonstrates their efficacy in delaying tumor growth in a breast cancer model.

bioRxiv · May 30, 2020Biochemistry

The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

L. J. Lahey, X. Wen, R. E. Mardjuki, V. Böhnert, G. T. Hess, C. Ritchie, J. A. Carozza, M. Maduke, M. C. Bassik, L. Li

The paper identifies LRRC8A:C as a cGAMP transporter in human vasculature cells and shows it mediates cGAMP import/export and is the dominant importer in these cells.

bioRxiv · Feb 13, 2020 · PreprintBiochemistry