Author

G. V. Pusapati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

R. Rohatgi· 3 shared M. Kinnebrew· 2 shared A. M. Lebensohn· 1 shared A. Radhakrishnan· 1 shared B. B. Patel· 1 shared B. Patel· 1 shared C. B. Khandwala· 1 shared C. Siebold· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

R. Rohatgi

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3 papers

Recent·Most cited

Direct ionic stress sensing and mitigation by the transcription factor NFAT5

C. B. Khandwala, P. Sarkar, H. B. Schmidt, M. Ma, M. Kinnebrew, G. V. Pusapati, B. B. Patel, D. Tillo, A. M. Lebensohn, R. Rohatgi

This study identifies NFAT5 as a direct sensor and effector of ionic stress in animal cells, showing it forms condensates to activate genes restoring ion balance.

bioRxiv · Sep 23, 2023Cell Biology

Sphingomyelin suppresses Hedgehog signaling by restricting cholesterol accessibility at the ciliary membrane

M. Kinnebrew, E. J. Iverson, B. Patel, G. V. Pusapati, J. H. Kong, K. A. Johnson, G. Luchetti, D. Covey, C. Siebold, A. Radhakrishnan, R. Rohatgi

This study identifies sphingomyelin's role in restricting cholesterol accessibility at the ciliary membrane, thereby suppressing Hedgehog signaling.

bioRxiv · Jul 16, 2019 · PreprintCell Biology

Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling

S.-R. Hong, C.-L. Wang, Y.-S. Huang, Y.-C. Chang, Y.-C. Chang, G. V. Pusapati, C.-Y. Lin, N. Hsu, H.-C. Cheng, Y.-C. Chiang, W.-E. Huang, N. C. Shaner, R. Rohatgi, T. Inoue, Y.-C. Lin

The paper develops a method to rapidly deplete tubulin glutamylation in primary cilia, revealing its role in intraflagellar transport and Hedgehog signaling without affecting other PTMs.

bioRxiv · Mar 15, 2018Cell Biology