Concerted cellular responses to type I interferon propel memory impairment associated with amyloid β plaques
Ethan R. Roy, Gabriel S. Chiu, Sanming Li, Nicholas E. Propson, Hui Zheng, Wei Cao
This study identifies type I interferon signaling as a key driver of memory impairment in Alzheimer's disease by promoting neuroinflammation and synaptic loss in a mouse model.
bioRxiv · Nov 1, 2021 · PreprintNeuroscience