Author

Gemma L. Curie

Innovative Genomics Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alexander MarsoniD· 2 shared Benjamin G. GoweniD· 2 shared Dimitre R. SimeonoviD· 2 shared Jacob E. CorniD· 2 shared Alice Y. K. ChaniD· 1 shared Andy Y. CheniD· 1 shared Ansuman T. SatpathyiD· 1 shared Carinna Tran· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

Alexander MarsonORCID

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Author profile →

2 papers

Recent·Most cited

Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3

Jennifer M. Umhoefer, Maya M. Arce, Sivakanthan Kasinathan, Sean Whalen, Rama Dajani, Sanjana Subramanya, Laine Goudy, Julia A. Belk, Royce W. Zhou, Minh T.N. Pham, Wenxi Zhang, Rosmely Hernandez, Carinna Tran, Nikhita Kirthivasan, Jacob W. Freimer, , Alexander Marson

The paper identifies cis-regulatory elements and transcription factors controlling FOXP3 expression in human Tregs and Tconvs, revealing mechanisms that restrict FOXP3 to Tregs in mice.

Immunity · Nov 13, 2025Peer-reviewedImmunology

Discovery of an autoimmunity-associated IL2RA enhancer by unbiased targeting of transcriptional activation

Dimitre R. Simeonov, Benjamin G. Gowen, Mandy Y. Boontanrart, Theodore L. Roth, Youjin Lee, Alice Y. K. Chan, Michelle Ly Thai Nguyen, Rachel E. Gate, Meena Subramaniam, Jonathan M. Woo, Therese Mitros, Graham J. Ray, Nicolas Bray, Gemma L. Curie, Nicki Naddaf, , Alexander Marson

The paper identifies an IL2RA enhancer associated with autoimmunity using CRISPRa and shows it affects gene activation timing without blocking expression.

bioRxiv · Dec 5, 2016 · PreprintGenetics