Single nucleus multi-omic atlas of human dorsal root ganglia reveals the contribution of nonneuronal cell types to pain
Guoyan Zhao, Kevin Boyer, Pauline Meriau, Lite Yang, Huma Umber Naz, Sarah F. Rosen, George Murray, Adam J. Dourson, Juliet M. Mwirigi, John Smith Del Rosario, Maria Payne, Prashant Gupta, Jiwon Yi, Richard A. Slivicki, Zachariah Bertels, , Valeria Cavalli
This study creates a single-nucleus multi-omic atlas of human dorsal root ganglia, identifying novel regulatory mechanisms and therapeutic targets for pain.
bioRxiv · Sep 21, 2025 · PreprintNeuroscience