Jiwon Yi

This paper creates a multi-omic atlas of human autonomic and sensory ganglia, identifying cell-type-specific features and disease associations in peripheral neuropathies.

This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.

This study creates a single-nucleus multi-omic atlas of human dorsal root ganglia, identifying novel regulatory mechanisms and therapeutic targets for pain.

This study links electrical properties to transcriptional identities in human sensory neurons, identifying associations between pain history and specific electrophysiological subtypes.

The paper investigates FGFR3 expression in human peripheral nervous system tissues and finds no detectable mRNA or protein expression in nerve or dorsal root ganglia, suggesting FGFR3 autoantibodies may not directly cause neuropathy.

The paper builds harmonized cross-species cell atlases of DRG and TG, identifies 29 cell types across 6 species, and shows transcriptomic similarities and differences in sensory neurons.

This study characterizes bradykinin receptor expression and function in human dorsal root ganglia neurons, finding conserved acute hyperexcitability and age/pain history-related B1 receptor expression.

This study evaluates CB-13, a peripherally selective CB1 agonist, showing it reduces pain in mice but develops tolerance and CNS effects with repeated dosing.

The paper shows that microglia perform local protein synthesis in peripheral processes to support phagocytic activity and lysosomal machinery assembly.