Potent Neutralization by Antibodies Targeting the Mpox A28 Protein
Ron Yefet, Leandro Battini, Mathieu Hubert, Katya Rakayev, Florence Guivel‐Benhassine, Noam Rattner, Françoise Porrot, Lilach Abramovitz, Gilad Ostashinsky, Noam Ben-Shalom, Jeanne Postal, Ksenia Polonsky, Maya Ralph-Altman, Sireen Sweed, T. W. Körner, , Natalia Tarnovitski Freund
The paper identifies and characterizes monoclonal antibodies targeting the Mpox A28 protein, showing potent neutralization of Mpox and Vaccinia virus through complement-dependent mechanisms and providing protection in mice.
bioRxiv · May 22, 2025 · PreprintImmunology