HSV-1 hijacks the DNA repair protein RAD51 at gene promoters to drive viral transcription
Namrata Kumar, Laura E. M. Dunn, Tanner M. Tessier, Katharina E. Hayer, Sireen Sweed, Maya Ralph-Altman, Holly Chan, Brandon G. Waxman, Edwin Halko, Yuval Altman, Jonathan Korner, Oren Kobiler, Joel D. Baines, Matthew D. Weitzman
This study shows HSV-1 uses RAD51 to enhance viral gene expression by binding to promoter regions and interacting with ADNP.
bioRxiv · Jul 10, 2026 · PreprintCell Biology