Author

Noam Ben-Shalom

Tel Aviv UniversityORCID 0000-0002-5780-3264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Ksenia PolonskyiD· 2 shared Lilach AbramovitziD· 2 shared Natalia Tarnovitski FreundiD· 2 shared Ron YefetiD· 2 shared Carmit LevyiD· 1 shared Dafna Tussia-CoheniD· 1 shared David HaginiD· 1 shared Eli SprecheriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Ksenia PolonskyORCID

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2 papers

Recent·Most cited

Decoy Antibodies Block Extracellular HSP70, Prevent Self Signaling and Inhibit Melanoma Cell Survival

Noam Ben-Shalom, Shivang Parikh, Lilach Abramovitz, Ron Yefet, Paulee Manich, Dafna Tussia-Cohen, Ori Moskowitz, Roma Parikh, Stav Melamed, Ksenia Polonsky, Sébastien Apcher, Tzachi Hagai, Merav Cohen, Yochai Wolf, Ronnie Shapira‐Frommer, , Natalia Tarnovitski Freund

This study identifies decoy antibodies targeting extracellular HSP70 on melanoma-derived melanosomes, which inhibit tumor growth and survival in preclinical models and correlate with clinical response to immunotherapy.

Cell Reports · Apr 22, 2026Peer-reviewedImmunology

Potent Neutralization by Antibodies Targeting the Mpox A28 Protein

Ron Yefet, Leandro Battini, Mathieu Hubert, Katya Rakayev, Florence Guivel‐Benhassine, Noam Rattner, Françoise Porrot, Lilach Abramovitz, Gilad Ostashinsky, Noam Ben-Shalom, Jeanne Postal, Ksenia Polonsky, Maya Ralph-Altman, Sireen Sweed, T. W. Körner, , Natalia Tarnovitski Freund

The paper identifies and characterizes monoclonal antibodies targeting the Mpox A28 protein, showing potent neutralization of Mpox and Vaccinia virus through complement-dependent mechanisms and providing protection in mice.

bioRxiv · May 22, 2025 · PreprintImmunology