Author

Lilach Abramovitz

Tel Aviv UniversityORCID 0000-0001-9961-9986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Approach:wet-lab / biochemical assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

Natalia Tarnovitski FreundiD· 3 shared Katya Rakayev· 2 shared Ksenia PolonskyiD· 2 shared Noam Ben-ShalomiD· 2 shared Ron YefetiD· 2 shared Adam Fillion· 1 shared Avia Watson· 1 shared Babak JavidiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

Natalia Tarnovitski FreundORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Decoy Antibodies Block Extracellular HSP70, Prevent Self Signaling and Inhibit Melanoma Cell Survival

Noam Ben-Shalom, Shivang Parikh, Lilach Abramovitz, Ron Yefet, Paulee Manich, Dafna Tussia-Cohen, Ori Moskowitz, Roma Parikh, Stav Melamed, Ksenia Polonsky, Sébastien Apcher, Tzachi Hagai, Merav Cohen, Yochai Wolf, Ronnie Shapira‐Frommer, , Natalia Tarnovitski Freund

This study identifies decoy antibodies targeting extracellular HSP70 on melanoma-derived melanosomes, which inhibit tumor growth and survival in preclinical models and correlate with clinical response to immunotherapy.

Cell Reports · Apr 22, 2026Peer-reviewedImmunology

Early Antibody-Mediated Immunity to Tuberculosis in Mice Requires NLRP3

Rania Bouzeyen, Nyaradzai Sithole, Avia Watson, Lilach Abramovitz, Katya Rakayev, Adam Fillion, Tessa Dickson, Paul A. MacAry, Patricia A. Darrah, Robert A. Seder, Natalia Tarnovitski Freund, Babak Javid

This study shows that antibodies against Mtb enhance immunity via NLRP3 inflammasome activation in mice, independent of Fc receptors, and this mechanism applies to polyclonal sera in rhesus macaques.

bioRxiv · Jul 18, 2025 · PreprintImmunology

Potent Neutralization by Antibodies Targeting the Mpox A28 Protein

Ron Yefet, Leandro Battini, Mathieu Hubert, Katya Rakayev, Florence Guivel‐Benhassine, Noam Rattner, Françoise Porrot, Lilach Abramovitz, Gilad Ostashinsky, Noam Ben-Shalom, Jeanne Postal, Ksenia Polonsky, Maya Ralph-Altman, Sireen Sweed, T. W. Körner, , Natalia Tarnovitski Freund

The paper identifies and characterizes monoclonal antibodies targeting the Mpox A28 protein, showing potent neutralization of Mpox and Vaccinia virus through complement-dependent mechanisms and providing protection in mice.

bioRxiv · May 22, 2025 · PreprintImmunology