Author

H. A. Dobrila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. J. Hryckowian· 2 shared D. Pensinger· 2 shared A. T. Fisher· 1 shared B. Schumann· 1 shared C. Bertozzi· 1 shared C. Martin· 1 shared D. Amador-Noguez· 1 shared D. M. Stevenson· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. J. Hryckowian

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in Clostridioides difficile

D. Pensinger, H. A. Dobrila, D. M. Stevenson, N. M. Davis, D. Amador-Noguez, A. J. Hryckowian

This study shows exogenous butyrate inhibits C. difficile growth by interfering with its own butyrate production and alters virulence gene expression.

bioRxiv · Jul 6, 2023 · PreprintMicrobiology

Butyrate differentiates permissiveness to Clostridioides difficile infection and influences growth of diverse C. difficile isolates

D. Pensinger, A. T. Fisher, H. A. Dobrila, W. Van Treuren, J. O. Gardner, S. K. Higginbottom, M. M. Carter, B. Schumann, C. Bertozzi, V. Anikst, C. Martin, E. Robilotti, J. Chow, R. H. Buck, L. S. Tompkins, , A. J. Hryckowian

This study shows butyrate reduces C. difficile fitness in mice and humans, and inhibits growth of diverse C. difficile isolates, suggesting dietary interventions could help prevent CDI.

bioRxiv · May 20, 2022Microbiology