R. Grant

Barriers to cascade screening in people at risk of Thoracic Aortic Disease: a mixed methods evaluation from the DECIDE-TAD initiative

This study identifies barriers to cascade screening for thoracic aortic disease using mixed methods, finding low uptake due to awareness, health literacy, and cost concerns.

Lung injury induces alveolar type 2 cell hypertrophy and polyploidy with implications for repair and regeneration

This study shows lung injury induces alveolar type 2 cell hypertrophy and polyploidy, which can be reduced by inhibiting the integrated stress response.

Spatiotemporal variations in retrovirus-host interactions among Darwin's finches

The paper examines spatiotemporal variations in retrovirus-host interactions among Darwin's finches, revealing shared ERVs pre-dating speciation and population-specific ERV variation linked to historical gene flow and speciation.

Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1

This study redefines AURKA degron motifs, showing the N-terminal A-box functions as a D-box and the C-terminal D-box is not a degron but a structural motif essential for AURKA's active conformation.

Dissociating the effects of distraction and proactive interference on object memory through tests of novelty preference

This paper demonstrates that two variants of the novel object recognition task can dissociate distraction and proactive interference effects in a schizophrenia model.

AURKA destruction is decoupled from its activity at mitotic exit but suppresses interphase activity

The paper investigates AURKA activity regulation, finding that its inactivation at mitotic exit depends on TPX2 degradation, not AURKA destruction, and that FZR1 suppresses interphase AURKA activity.

Assessing metadata and curation quality: a case study from the development of a third-party curation service at Springer Nature

The paper describes a project to assess metadata quality during the development of a third-party curation service for research data.

The impact on authors and editors of introducing Data Availability Statements at Nature journals

Regulation of mitochondrial dynamics by Aurora A kinase

This study shows that Aurora A kinase associates with mitochondria and influences their dynamics, affecting mitochondrial morphology in different cell lines.