Author

H. Chakrapani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Singh· 2 shared S. Singh· 2 shared A. Akhir· 1 shared A. T. Kumar· 1 shared A. Tripathi· 1 shared C. Thakur· 1 shared G. Kaul· 1 shared J. Hirschi· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

A. Singh

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

An Arm-to-Disarm Strategy to Overcome Phenotypic AMR in Mycobacterium tuberculosis

T. A. Kumar, S. Birua, S. C. M, P. Mukherjee, S. Singh, G. Kaul, A. Akhir, S. Chopra, J. Hirschi, A. Singh, H. Chakrapani

This paper develops a prodrug strategy to overcome phenotypic AMR in Mtb by enhancing drug permeability and targeting hypoxic persisters.

bioRxiv · Mar 23, 2023Microbiology

Moxifloxacin-mediated killing of Mycobacterium tuberculosis involves respiratory downshift, reductive stress, and ROS accumulation

S. Shee, S. Singh, A. Tripathi, C. Thakur, A. T. Kumar, M. Das, V. Yadav, S. Kohli, R. S. Rajmani, N. Chandra, H. Chakrapani, K. drlica, A. Singh

This study identifies moxifloxacin-induced oxidative stress in Mycobacterium tuberculosis as a mechanism of killing, showing that reductive stress and iron contribute to ROS accumulation and drug efficacy.

bioRxiv · Apr 4, 2022 · PreprintMicrobiology