An Arm-to-Disarm Strategy to Overcome Phenotypic AMR in Mycobacterium tuberculosis
T. A. Kumar, S. Birua, S. C. M, P. Mukherjee, S. Singh, G. Kaul, A. Akhir, S. Chopra, J. Hirschi, A. Singh, H. Chakrapani
This paper develops a prodrug strategy to overcome phenotypic AMR in Mtb by enhancing drug permeability and targeting hypoxic persisters.
bioRxiv · Mar 23, 2023Microbiology