Author

H. Djaballah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Liu· 1 shared A. Nagelberg· 1 shared C. Brandstadter· 1 shared C. Radu· 1 shared D. Fansworth· 1 shared D. Lu· 1 shared D. Shum· 1 shared F. D. Johnson· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Liu

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2 papers

Recent·Most cited

Antiproliferative Activity of Cephalotaxus Esters: Overcoming Chemoresistance in Cancer Therapy

V. Yong-Gonzalez, C. Radu, P. A. Calder, D. Shum, M. G. Frattini, H. Djaballah

This study evaluates the antiproliferative effects of HHT and its derivatives against cancer cells, finding that they overcome MDR1-mediated resistance in some cell lines but are effective against primary leukemia cells.

bioRxiv · Nov 6, 2023 · PreprintPharmacology & Toxicology

A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

F. D. Johnson, J. Ferrarone, A. Liu, C. Brandstadter, R. Munuganti, D. Fansworth, D. Lu, J. Luu, T. Sihota, S. Jansen, A. Nagelberg, R. Shi, G. C. Forcina, X. Zhang, G. S. W. Cheng, , W. W. Lockwood

The paper identifies LCS3, a compound that induces oxidative stress in lung cancer cells by inhibiting disulfide reductases GSR and TXNRD1, and shows its synergistic effect with glutathione and thioredoxin pathway inhibition.

bioRxiv · Jun 28, 2021 · PreprintCancer Biology