Author

H. Holthusen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. W. Sanders· 1 shared F.-U. Hartl· 1 shared I. Dudanova· 1 shared I. Saha· 1 shared M. da Silva Padilha· 1 shared M. I. Diamond· 1 shared M. S. Hipp· 1 shared P. Yuste-Checa· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

D. W. Sanders

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds

I. Saha, P. Yuste-Checa, M. da Silva Padilha, Q. Guo, R. Körner, H. Holthusen, V. A. Trinkaus, I. Dudanova, R. Fernandez-Busnadiego, W. Baumeister, D. W. Sanders, S. Gautam, M. I. Diamond, F.-U. Hartl, M. S. Hipp

This study shows that the AAA+ chaperone VCP disaggregates Tau fibrils and generates seeding-active Tau as a byproduct, suggesting a role in aggregate removal and spreading in tauopathies.

bioRxiv · Feb 18, 2022Cell Biology