Structural basis for ion selectivity in potassium-selective channelrhodopsins
S. Tajima, Y. S. Kim, M. Fukuda, E. F. X. Byrne, P. Y. Wang, J. M. Paggi, K. E. Kishi, C. Ramakrishnan, S. Takaramoto, T. Nagata, M. Konno, M. Sugiura, K. Katayama, T. E. Matsui, K. Yamashita, , H. E. Kato
The paper determines the cryo-EM structures of two K+-selective channelrhodopsins, revealing a unique mechanism for K+ selectivity distinct from canonical K+ channels.
bioRxiv · Oct 30, 2022Biophysics