T. Satoh

RudLOV-a new optically synchronized cargo transport method reveals unexpected effect of dynasore

The paper introduces RudLOV, an optical method for synchronized cargo release, revealing dynasore's differential effects on early and late Golgi transport.

CiDRE+ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity

This study identifies IL-10-driven M2c macrophages as key contributors to severe COVID-19 by facilitating SARS-CoV-2 infection and highlights CiDRE as a potential therapeutic target.

Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade

This study investigates the self-assembling properties of CAHS1 protein from tardigrades under desiccation conditions, showing it forms hydrogels and condensates that may contribute to desiccation tolerance.

Human DC3 Antigen Presenting Dendritic Cells from Induced Pluripotent Stem Cells

This paper describes the generation of human DC3 antigen-presenting cells from induced pluripotent stem cells and examines the effect of JAK2 V617F mutations on their differentiation.

Lipooligosaccharide, Vag8, and pertussis toxin of Bordetella pertussis cooperatively cause coughing in mice

The paper develops a mouse model of whooping cough and identifies that LOS, Vag8, and PTx cooperatively cause coughing by modulating TRPV1 and bradykinin levels.

Characterization of amyloid β fibril formation under microgravity conditions

This study examines amyloid β fibril formation under microgravity conditions on the ISS, finding slower progression and distinct morphologies compared to ground-based experiments.

A Rab11-GEF Parcas recruits Rab11 onto recycling endosomes for rhodopsin transport in Drosophila photoreceptors

This study identifies Parcas as a Rab11-GEF critical for recruiting Rab11 to recycling endosomes and post-Golgi vesicles in Drosophila photoreceptors, with its loss causing rhodopsin accumulation similar to Rab11 deficiency.

USP15 participates in HCV propagation through the regulation of viral RNA translation and lipid droplet formation

This study identifies USP15 as a host factor for HCV propagation, showing it regulates viral RNA translation and lipid droplet formation in hepatic cells.