Author

H. Ingle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. T. Baldridge· 2 shared A. H. Kim· 1 shared A. Hassan· 1 shared A. P. Wright· 1 shared C. Desai· 1 shared D. A. Constant· 1 shared E. A. Kennedy· 1 shared J. A. Van Winkle· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

M. T. Baldridge

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2 papers

Recent·Most cited

Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination

Y. Li, J. M. Molleston, A. H. Kim, H. Ingle, S. Aggarwal, L. Nolan, A. Hassan, L. Foster, M. Diamond, M. T. Baldridge

This study shows that sequential early-life viral infections in mice reduce antibody responses to SARS-CoV-2 vaccination while altering immune cell profiles and gut microbiota.

bioRxiv · Aug 31, 2023Microbiology

A homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

J. A. Van Winkle, S. T. Peterson, E. A. Kennedy, M. J. Wheadon, H. Ingle, C. Desai, R. Rodgers, D. A. Constant, A. P. Wright, L. Li, M. Artyomov, S. Lee, M. T. Baldridge, T. J. Nice

The paper shows bacterial microbiota induce localized IFN-lambda-driven antiviral defenses in intestinal epithelial cells, enhancing host resistance to enteric viruses.

bioRxiv · Jun 2, 2021Immunology