Author

E. A. Kennedy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. T. Baldridge· 4 shared R. Rodgers· 2 shared A. Bendesky· 1 shared A. O. Kolawole· 1 shared A. P. Wright· 1 shared C. Desai· 1 shared C. Wilen· 1 shared C. Wobus· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersMicrobiology

M. T. Baldridge

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Microbiota produced indole metabolites disrupt host cell mitochondrial energy production and inhibit Cryptosporidium parvum growth

L. Funkhouser-Jones, R. Xu, G. Wilke, Y. Fu, L. A. Shriefer, H. Makimaa, R. Rodgers, E. A. Kennedy, K. VanDussen, T. Stappenbeck, M. T. Baldridge, L. D. Sibley

The paper identifies indole metabolites from the microbiota that inhibit Cryptosporidium parvum growth by disrupting host mitochondrial function and parasite mitosome membrane potential.

bioRxiv · May 25, 2023 · PreprintMicrobiology

Genetic mapping reveals Pou2af2-dependent tuning of tuft cell differentiation and intestinal type 2 immunity

M. S. Nadjsombati, N. Niepoth, L. M. Webeck, E. A. Kennedy, D. L. Jones, M. T. Baldridge, A. Bendesky, J. von Moltke

The paper identifies Pou2af2 isoform usage as a regulator of tuft cell differentiation and intestinal type 2 immunity through genetic mapping in mice.

bioRxiv · Oct 19, 2022 · PreprintImmunology

A homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

J. A. Van Winkle, S. T. Peterson, E. A. Kennedy, M. J. Wheadon, H. Ingle, C. Desai, R. Rodgers, D. A. Constant, A. P. Wright, L. Li, M. Artyomov, S. Lee, M. T. Baldridge, T. J. Nice

The paper shows bacterial microbiota induce localized IFN-lambda-driven antiviral defenses in intestinal epithelial cells, enhancing host resistance to enteric viruses.

bioRxiv · Jun 2, 2021Immunology

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

V. Graziano, F. C. Walker, E. A. Kennedy, J. Wei, K. Ettayebi, M. Simoes, R. Filler, E. Hassan, L. L. Hsieh, A. O. Kolawole, C. Wobus, L. C. Lindesmith, R. S. Baric, M. Estes, R. C. Orchard, , C. Wilen

This paper identifies CD300lf as the primary receptor for murine norovirus in vivo but shows it is not used by human norovirus.

PLOS Pathogens · Apr 6, 2020Peer-reviewedMicrobiology

Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids

S. C. Di Rienzi, J. Jacobson, E. A. Kennedy, M. E. Bell, Q. Shi, J. L. Waters, P. Lawrence, J. T. Brenna, R. A. Britton, J. Walter, R. E. Ley

This study shows that small intestinal lactobacilli can resist the toxicity of soybean oil fatty acids through environmental protection and evolutionary adaptation.

bioRxiv · Mar 15, 2018Microbiology