Author

A. H. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Organism:human· 6 Research Focus:differential expression· 5 Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Research Focus:cell-cell communication· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3

Frequent Co-Authors

M. R. Chicoine· 3 shared A. A. Petti· 2 shared A. J. Livingstone· 2 shared A. Z. Wang· 2 shared E. C. Leuthardt· 2 shared G. J. Zipfel· 2 shared G. P. Dunn· 2 shared J. W. Osbun· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

M. R. Chicoine

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination

Y. Li, J. M. Molleston, A. H. Kim, H. Ingle, S. Aggarwal, L. Nolan, A. Hassan, L. Foster, M. Diamond, M. T. Baldridge

This study shows that sequential early-life viral infections in mice reduce antibody responses to SARS-CoV-2 vaccination while altering immune cell profiles and gut microbiota.

bioRxiv · Aug 31, 2023Microbiology

Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population

A. Z. Wang, B. L. Mashimo, M. O. Schaettler, N. D. Sherpa, L. A. Leavitt, A. J. Livingstone, S. M. Khan, M. Li, M. Anzaldua-Campos, J. D. Bradley, E. C. Leuthardt, A. H. Kim, J. L. Dowling, M. R. Chicoine, P. S. Jones, , G. P. Dunn

The paper analyzes TILs in GBM using CITE-seq and scRNA-seq to show that CD8+ T cells are predominantly clonally expanded GZMK+ effector cells, lacking canonical exhaustion.

bioRxiv · Aug 25, 2023 · PreprintImmunology

Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

T. F. Barrett, B. Patel, S. M. Khan, A. K. Y. Yim, S. Pugazenthi, T. Mahlokozera, R. D. Z. Mullins, G. J. Zipfel, J. A. Herzog, M. R. Chicoine, C. C. Wick, N. Durakovic, J. W. Osbun, M. Shew, A. D. Sweeney, , A. H. Kim

The paper analyzes single-cell multi-omic data from vestibular schwannomas to identify a nerve injury-like state in tumor-associated Schwann cells linked to myeloid cell recruitment and tumor growth.

bioRxiv · Nov 18, 2022Cancer Biology

Gonadal sex patterns p21-induced cellular senescence in mouse and human glioblastoma

L. Broestl, L. Grandison, S. Shenoy, M. M. Tallman, G. Rhee, W. Yang, J. Sponagel, N. Kfoury-Beaumont, C. M. Hill, D. D. Mao, A. H. Kim, S. A. Stewart, M. Venere, J. Luo, J. B. Rubin

The paper shows that gonadal sex influences p21-induced cellular senescence in GBM, contributing to sex differences in survival.

Communications Biology · Aug 2, 2022Peer-reviewedCancer Biology

The conventional dendritic cell 1 subset primes CD8+ T cells and traffics tumor antigen to drive anti-tumor immunity in the brain

J. A. Bowman-Kirigin, B. T. Saunders, R. Desai, A. Z. Wang, M. O. Schaettler, C. J. Liu, A. J. Livingstone, D. K. Kobayashi, V. Durai, N. M. Kretzer, G. J. Zipfel, E. C. Leuthardt, J. W. Osbun, M. R. Chicoine, A. H. Kim, , G. P. Dunn

The paper identifies cDC1's role in priming CD8+ T cells and trafficking tumor antigens to drive anti-tumor immunity in the brain.

bioRxiv · Sep 13, 2021Immunology

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.

L. Ma, S. K. Sahu, M. Cano, V. Kuppuswamy, J. Bajwa, J. McPhatter, A. B. Pine, M. M. Meizlish, G. Goshua, C. H. Chang, H. Zhang, C. Price, P. Bahel, H. M. Rinder, T. Lei, , H. S. Kulkarni

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.

bioRxiv · Feb 22, 2021Immunology

Spatial drivers and pre-cancer populations collaborate with the microenvironment in untreated and chemo-resistant pancreatic cancer

D. Cui Zhou, R. G. Jayasinghe, J. M. Herndon, E. Storrs, C.-K. Mo, Y. Wu, R. S. Fulton, M. A. Wyczalkowski, C. C. Fronick, L. A. Fulton, L. Thammavong, K. Sato, H. Zhu, H. Sun, L.-B. Wang, , Ch

This paper uses spatial single-cell omics to analyze PDAC tumors and microenvironment, identifying key populations and interactions that may inform treatment strategies.

bioRxiv · Jan 13, 2021Cancer Biology