T. Nishiyama

Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production

This study identifies a direct relationship between viral protein expression and progeny yield in herpes simplex virus 1, revealing DNA cleavage/packaging as a rate-limiting step for virus production.

Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation for analyzing extracellular viral markers

This study develops a multiscale mathematical model to predict intrahepatic cccDNA dynamics using serum viral markers, offering a non-invasive method for HBV infection analysis.

Extensive Copy Number Variation Explains Genome Size Variation in the Unicellular Zygnematophycean Alga, Closterium peracerosum-strigosum-littorale Complex

This study identifies genome size variation in the alga Closterium psl. complex as primarily due to copy number variation, with nonrandom distribution of CNV across gene functions.

Diversity of genome size and chromosome number in homothallic and heterothallic strains of the Closterium peracerosum-strigosum-littorale complex (desmidiales, zygnematophyceae, streptophyta)

This study compares genome size and chromosome number between homothallic and heterothallic strains of the Closterium psl complex, finding positive correlations with cell size and chromosomal variation within mating groups.

Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit

This study shows that the N-terminal tail of CAP-H regulates condensin I loading in a cell cycle-specific manner through phosphorylation and deletion effects in Xenopus extracts.

Prediction of elimination of intrahepatic cccDNA in hepatitis B virus-infected patients by a combination of noninvasive viral markers

This study develops a noninvasive method using viral markers to predict cccDNA levels in HBV patients, validated against liver biopsy data.

SORORIN is an evolutionary conserved antagonist of WAPL

This study identifies SORORIN orthologs in yeast and plants, showing they antagonize WAPL to maintain cohesion, with tissue-specific functions in plants.

An ancestral function of strigolactones as symbiotic rhizosphere signals

This study identifies BSB, an ancestral strigolactone in bryophytes, which functions as a rhizosphere signal for AM symbiosis and was later co-opted as a plant hormone.

Phylogenetic distribution and expression pattern analyses identified a divergent basal body assembly protein involved in land plant spermatogenesis

The paper identifies a divergent BLD10 protein involved in land plant spermatogenesis through evolutionary and molecular genetic analyses.

Discovery of the fastest myosin, its amino acid sequence, and structural features

The paper identifies CbXI-1 as the fastest myosin with a velocity of 73 m s-1, cloned from Chara braunii, and reports its atomic structure and structural features contributing to high-speed movement.

A simple Agrobacterium-mediated stable transformation technique for the hornwort model Anthoceros agrestis

This paper develops a stable transformation technique for the hornwort Anthoceros agrestis using Agrobacterium, enabling genetic studies of molecular mechanisms in land plants.

Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus

This study sequenced the genome of a kleptoplastic sea slug and found no evidence of algal gene transfer to the nucleus, showing photosynthesis can occur without nuclear gene transfer.

Toward Health Management of Major Labour Force Generation by Using Infection Control Countermeasures for Haematobium Schistosomiasis -assumed to be related to occupational risk- in the Republic of Malawi

This study evaluates the effectiveness of praziquantel mass drug administration (MDA) and urine reagent strips for controlling haematobium schistosomiasis in Malawi's working-age population, showing significant prevalence reduction and cost-effectiveness.

Single-cell transcriptome analysis of Physcomitrella leaf cells during reprogramming using microcapillary manipulation

The paper introduces 1cell-DGE, a single-cell RNA-sequencing method using microcapillary manipulation to analyze gene expression in intact moss tissues, identifying differentially expressed genes during leaf cell reprogramming.

Patterns of polymorphism, selection and linkage disequilibrium in the subgenomes of the allopolyploid Arabidopsis kamchatica

The paper analyzes polymorphism, selection, and linkage disequilibrium in the subgenomes of Arabidopsis kamchatica, finding reduced purifying selection and increased adaptive substitutions compared to parental species.