Author

H. P. Bogerd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. R. Cullen· 3 shared C.-C. Chu· 2 shared H. M. Al-Hashimi· 2 shared L. R. Ganser· 2 shared M. L. Kelly· 2 shared A. Chalem· 1 shared B. A. Law· 1 shared B. Cullen· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiochemistry

B. R. Cullen

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Author profile →

4 papers

Recent·Most cited

Revealing the high propensity of RNAs to non-specifically bind drug-like small molecules

M. L. Kelly, C.-C. Chu, H. Shi, L. R. Ganser, H. P. Bogerd, K. Huynh, Y. Hou, B. R. Cullen, H. M. Al-Hashimi

This study examines the non-specific binding of three drug-like compounds to HIV-1 stem-loop RNAs, showing they inhibit RNA function and exhibit off-target interactions.

bioRxiv · May 2, 2020Biochemistry

Robust HIV-1 Replication in the Absence of Integrase Function.

I. D. Irwan, H. L. Karnowski, H. P. Bogerd, K. Tsai, B. Cullen

This study shows HIV-1 can replicate robustly without integrase function in cells expressing HTLV-1 Tax, forming transcriptionally active episomal DNA circles that avoid epigenetic silencing.

bioRxiv · Mar 18, 2020 · PreprintMicrobiology

Probing RNA conformational equilibria within the functional cellular context

L. R. Ganser, C.-C. Chu, H. P. Bogerd, M. L. Kelly, B. R. Cullen, H. M. Al-Hashimi

The paper develops a method to assess RNA excited-state stability and abundance in cells using mutations and applies it to HIV-1 regulatory RNAs, showing ESs form with comparable abundance in vitro and in vivo.

bioRxiv · Sep 1, 2019Biochemistry

Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression

D. Courtney, A. Chalem, H. P. Bogerd, B. A. Law, E. M. Kennedy, C. L. Holley, B. R. Cullen

This study shows that murine leukemia virus (MLV) transcripts have high levels of m6A, m5C, and Nm modifications, which enhance viral replication and gene expression.

bioRxiv · Mar 28, 2019Microbiology