Author

H. P. Kohio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. Ding· 2 shared A. Brown· 1 shared A. C. M. Boon· 1 shared A. L. Bailey· 1 shared B. Fan· 1 shared B. Li· 1 shared B. Niu· 1 shared E. D. Martinez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

S. Ding

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antiretroviral APOBEC3 Cytidine Deaminases Alter HIV-1 Provirus Integration Site Profiles

H. O. Ajoge, T. M. Renner, K. Belanger, H. P. Kohio, M. D. Coleman, M.-A. Langlois, S. D. Barr

This study shows APOBEC3 proteins alter HIV-1 integration site preferences by reducing insertions into genes and increasing them into SINE elements and non-B DNA regions.

Nature Communications · Jan 10, 2023Peer-reviewedMicrobiology

Molecular Basis for Interferon-mediated Pathogen Restriction in Human Cells

S. K. Matta, H. P. Kohio, P. Chandra, A. Brown, J. G. Doench, J. A. Philips, S. Ding, L. D. Sibley

This study identifies RNF213 as essential for IFN-gamma-mediated restriction of intracellular pathogens like Toxoplasma gondii and Mycobacterium tuberculosis through ubiquitination, independent of autophagy.

bioRxiv · Oct 21, 2022 · PreprintMicrobiology

JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis

J. Son, S. Huang, Q. Zeng, T. L. Bricker, J. B. Case, J. Zhou, R. Zang, Z. Liu, X. Chang, H. H. Harastani, L. Chen, M. F. Gomez Castro, Y. Zhao, H. P. Kohio, G. Hou, , S. Ding

The paper identifies JIB-04 as a broad-spectrum antiviral that inhibits SARS-CoV-2 replication and coronavirus pathogenesis in vitro and in vivo.

bioRxiv · Sep 24, 2020Microbiology