Author

R. Zang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

X. Wang· 4 shared M. S. Diamond· 3 shared P. W. Rothlauf· 3 shared Q. Zeng· 3 shared S. Ding· 3 shared S. P. J. Whelan· 3 shared Z. Liu· 3 shared G. Hou· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

X. Wang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Decoding human in vitro terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cells

X. Wang, W. Zhang, S. Zhao, H. Yan, Z. Xin, T. Cui, R. Zang, L. Zhao, H. Wang, J. Zhou, X. Li, W. Yue, J. Xi, Z. Zhang, X. Fang, X. Pei

This study maps ex vivo terminal erythropoiesis from umbilical cord blood mononuclear cells and pluripotent stem cells, identifying differences in regulatory dynamics and CD99 expression affecting erythroid expansion and maturation.

bioRxiv · Apr 20, 2023 · PreprintCell Biology

Noninvasive cancer detection by extracting and integrating multi-modal data from whole-methylome sequencing of plasma cell-free DNA

F. Bie, Z. Wang, Y. Li, Y. Hong, T. Han, F. Lv, S. Yang, S. Li, X. Li, P. Nie, R. Zang, M. Zhang, P. Song, F. Feng, W. Guo, , S. Gao

This paper develops a method to detect cancer noninvasively by integrating methylation, fragmentation, and copy number data from plasma cell-free DNA using machine learning.

bioRxiv · Jul 4, 2022 · PreprintCancer Biology

JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis

J. Son, S. Huang, Q. Zeng, T. L. Bricker, J. B. Case, J. Zhou, R. Zang, Z. Liu, X. Chang, H. H. Harastani, L. Chen, M. F. Gomez Castro, Y. Zhao, H. P. Kohio, G. Hou, , S. Ding

The paper identifies JIB-04 as a broad-spectrum antiviral that inhibits SARS-CoV-2 replication and coronavirus pathogenesis in vitro and in vivo.

bioRxiv · Sep 24, 2020Microbiology

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

S. Ding, R. Zang, J. B. Case, M. F. Gomez Castro, Z. Liu, Q. Zeng, H. Zhao, J. Son, P. W. Rothlauf, G. Hou, S. Bose, X. Wang, M. D. Vahey, T. Kirchhausen, D. H. Fremont, , S. P. J. Whelan

The paper identifies CH25H and its product 25HC as inhibitors of SARS-CoV-2 replication by blocking membrane fusion.

bioRxiv · Jun 8, 2020Microbiology

TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes

R. Zang, M. F. G. Castro, B. T. McCune, Q. Zeng, P. W. Rothlauf, N. M. Sonnek, Z. Liu, K. F. Brulois, X. Wang, H. B. Greenberg, M. S. Diamond, M. A. Ciorba, S. P. J. Whelan, S. Ding

This study shows SARS-CoV-2 infects human intestinal enterocytes via TMPRSS2 and TMPRSS4, but viral particles in stool are inactivated, suggesting limited fecal-oral transmission.

bioRxiv · Apr 21, 2020Microbiology