QSAR Model Based Gradient Boosting Regression of N-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Inhibitors for Fructose-1,6-Bisphosphatase
Z. Zhao, J. Yang, B. LI, T. Sun, H. Si, T. Ni
This study develops a Gradient Boosting Regression model to predict the inhibitory activity of N-Arylsulfonyl-Indole-2-Carboxamide derivatives against Fructose-1,6-Bisphosphatase, achieving high correlation and statistical significance.
bioRxiv · Aug 10, 2021Biochemistry