Author

H. Wakimoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. G. Seidman· 2 shared J. M. Gorham· 2 shared A. Antolic· 1 shared A. Cingoz· 1 shared A. Kayabolen· 1 shared A. P. Cribbs· 1 shared A. Saftics· 1 shared B. Isik· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

J. G. Seidman

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Author profile →

4 papers

Recent·Most cited

Exomap1 mouse: a transgenic model for in vivo studies of exosome biology

F. K. Fordjour, S. Abuelreich, X. Hong, E. Chatterjee, V. Lallai, M. Ng, A. Saftics, F. Deng, N. Carnel-Amar, H. Wakimoto, K. Shimizu, T. Anh Phu, N. K. Vu, P. C. Geiger, R. L. Raffai, , S. Gould

The exomap1 mouse model expresses HsCD81mNG to study exosome biology in vivo, showing cell type-specific exosome contributions and confirming CD81 as an exosome-specific marker.

bioRxiv · May 29, 2023 · PreprintCell Biology

Tbx5 maintains atrial identity by regulating an atrial enhancer network

M. E. Sweat, Y. Cao, X. Zhang, O. Burnicka-Turek, C. Perez-Cervantes, B. N. Akerberg, Q. Ma, H. Wakimoto, J. M. Gorham, M. K. Song, M. A. Trembley, P. Wang, F. Lu, M. Gianeselli, M. Prondzynski, , W. T. Pu

This study shows Tbx5 maintains atrial identity by regulating an atrial enhancer network through chromatin accessibility and looping.

bioRxiv · Apr 21, 2023Cell Biology

Orthogonal targeting of KDM6A/B and HDACs mediates potent therapeutic effects in IDH1-mutant glioma

A. Kayabolen, E. Yilmaz, G. N. Sahin, F. Seker-Polat, A. Cingoz, B. Isik, S. Acar, S. Karahuseyinoglu, H. Wakimoto, D. P. Cahill, I. Solaroglu, A. P. Cribbs, U. Oppermann, T. Bagci-Onder

This study identifies GSK-J4 and Belinostat as effective therapies for IDH1-mutant glioma by targeting KDM6A/B and HDACs, showing synergistic effects in vitro and in vivo.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

A. Antolic, H. Wakimoto, Z. Jiao, J. M. Gorham, S. R. DePalma, D. A. Conner, D. Y. Lee, J. Qi, J. G. Seidman, J. E. Bradner, J. D. Brown, S. M. Haldar, C. E. Seidman, M. A. Burke

This study shows BET bromodomain proteins drive inflammatory gene networks in cardiac fibroblasts, contributing to genetic dilated cardiomyopathy, and that JQ1, a BET inhibitor, reduces disease progression.

bioRxiv · Feb 9, 2020Cell Biology