Author

H. Y. Yeung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Safitri· 2 shared G. Ladds· 2 shared M. Harris· 2 shared A. Inoue· 1 shared B. Al-Zaid· 1 shared D. Bailey· 1 shared D. I. Mackie· 1 shared D. R. Poyner· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. Safitri

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintApr 8, 2021

RAMPs regulate signalling bias and internalisation of the GIPR

M. Harris, D. I. Mackie, J. B. Pawlak…·G. Ladds

This study shows RAMPs modulate GIPR signaling and internalization, with RAMP3 reducing cAMP production and promoting surface retention, while RAMP1/2 decrease Gq/11/15 activation, and RAMP1 is essential for normal glucose regulation.

DOI 10.1101/2021.04.08.436756

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivJul 30, 2019

Elevated intracellular cAMP concentration mediates growth suppression in glioma cells

D. Safitri, H. Potter, M. Harris…·G. Ladds

The paper shows that increasing intracellular cAMP levels via AC activation or PDE inhibition suppresses glioma cell growth, with different mechanisms depending on the PDE inhibitor used.

DOI 10.1016/j.bcp.2020.113823

mousebulk RNA-seq

𝕏 PostBluesky