Author

H.-B. Xin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. Fu· 2 shared T. Lei· 2 shared Y. Qian· 2 shared C. Lee· 1 shared H. Lin· 1 shared J. Qiu· 1 shared J. Wu· 1 shared K.-Y. Deng· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

M. Fu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

E3 ligase TRIM47 positively regulates endothelial activation and pulmonary inflammation through potentiating the K63-linked ubiquitination

Y. Qian, Z. Wang, H. Lin, T. Lei, Z. Zhou, W. Huang, X. Wu, L. Zuo, J. Wu, Y. Liu, L.-F. Wang, X.-H. Guan, K.-Y. Deng, M. Fu, H.-B. Xin

This study shows TRIM47 enhances endothelial activation and pulmonary inflammation by promoting K63-linked ubiquitination of TRAF2, leading to NF-κB and MAPK pathway activation.

bioRxiv · Sep 15, 2021 · PreprintCell Biology

Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin

Y. Qian, T. Lei, P. Patel, C. Lee, P. Monaghan-Nichols, H.-B. Xin, J. Qiu, M. Fu

This study identifies SARS-CoV-2 nucleocapsid protein as a potent activator of human endothelial cells, showing that simvastatin inhibits this activation through TLR2/NF-κB and MAPK pathways.

bioRxiv · Feb 14, 2021Immunology