Author

L. Zuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

X. Wu· 3 shared L. Li· 2 shared Z. WangiD· 2 shared B. Jiang· 1 shared C. Gao· 1 shared C. Wang· 1 shared C. Yue· 1 shared D. Deng· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersCell Biology

X. Wu

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Potential clinical value and influence of conductivity in conductive cardiac patches for reducing post-MI arrythmia risks

Y. Miao, Z. Fu, J. Zhang, Y. Tao, K. Pang, C. Wang, Q. Jiang, L. Shen, T. Xia, P. Lu, Z. Xu, L. Xia, L. Zuo, J. Song, C. Gao, , Y. Zhu

This study evaluates the clinical value of conductive cardiac patches by testing different conductivities and shows that higher conductivity reduces arrhythmia risks in post-MI hearts.

bioRxiv · Dec 27, 2023 · PreprintBioengineering

Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

S. D. Chanez-Paredes, S. Abtahi, J. Zha, L. Zuo, W. He, J. R. Turner

The paper identifies the Ig3 domain of MLCK1 as critical for perijunctional localization and barrier function, showing it can limit TNF-induced barrier loss in Crohn's disease.

bioRxiv · Oct 13, 2022 · PreprintCell Biology

E3 ligase TRIM47 positively regulates endothelial activation and pulmonary inflammation through potentiating the K63-linked ubiquitination

Y. Qian, Z. Wang, H. Lin, T. Lei, Z. Zhou, W. Huang, X. Wu, L. Zuo, J. Wu, Y. Liu, L.-F. Wang, X.-H. Guan, K.-Y. Deng, M. Fu, H.-B. Xin

This study shows TRIM47 enhances endothelial activation and pulmonary inflammation by promoting K63-linked ubiquitination of TRAF2, leading to NF-κB and MAPK pathway activation.

bioRxiv · Sep 15, 2021 · PreprintCell Biology

Genetic structure, function and evolution of capsule biosynthesis loci in Vibrio parahaemolyticus

S. Bian, Z. Wenhong, Q. Li, Y. Li, N.-K. Wong, M. Jiang, L. Zuo, Q. Hu, L. Li

This study identifies and characterizes the genetic structure and evolutionary relationships of CPS loci in 40 K-serogroups of Vibrio parahaemolyticus using whole genome sequencing of 443 strains.

Frontiers in Microbiology · Jan 11, 2021Peer-reviewedMicrobiology

Integrative Analysis the characterization of peroxiredoxins in pan-cancer

L. Gao, J. Meng, C. Yue, X. Wu, Q. Su, H. Wu, Z. Zhang, Q. Yu, S. Gao, S. Fan, L. Zuo

This study systematically analyzes peroxiredoxins (PRDXs) across 33 cancer types, examining expression, genetic alterations, methylation, prognosis, pathways, and drug targets, with validation of PRDX6's role in bladder cancer cell proliferation via JAK2-STAT3 pathway.

bioRxiv · Oct 9, 2020Cancer Biology

Rottlerin ameliorates DSS-induced colitis by improving intestinal barrier function via activation of the Epac-2/Rap-1 signaling pathway.

X. Song, L. Zuo, L. Wang, Z. Zhu, J. Tao, Y. Jiang, X. Wu, Z. Wang, J. Nian, P. Xiang, X. Zhang, H. Zhao, L. Yu, J. Li, J. Hu

This study shows rottlerin reduces DSS-induced colitis in mice by enhancing intestinal barrier function through the Epac-2/Rap-1 signaling pathway.

bioRxiv · Mar 16, 2020 · PreprintCell Biology

Effects of substrate stiffness on the biological behavior of human umbilical vein endothelial cells

H. Pei, L. Li, K. Liu, W. Wang, B. Jiang, Y. Li, L. Zuo

This study examines how substrate stiffness affects human umbilical vein endothelial cell behavior, finding increased CX40 and GAG content and decreased actin stress fibers and proliferation on stiff substrates.

bioRxiv · Oct 14, 2019 · PreprintCell Biology