Author

H.-Y. Fang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:Drosophila· 1 Organism:mouse· 1 Approach:simulation· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. Clarke· 2 shared E. Giniger· 2 shared A. Anand· 1 shared A. Chandrasekaran· 1 shared A. Proano-Vasco· 1 shared A. Schnieke· 1 shared D. Mohammad-Shahi· 1 shared E. McCreedy· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

A. Clarke

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Author profile →

3 papers

Recent·Most cited

KRas, in addition to Tp53 is a driver for early carcinogenesis and a molecular target in a mouse model of invasive gastro-esophageal adenocarcinoma

A. Anand, L. Schoemig, S. Lange, L. Tran, K. Flisikowski, R. Oellinger, R. Rad, M. Vieth, K. Steiger, T. Baumeister, J. Strangmann, H. Alguel, K. Ciecielski, K. Boettcher, H.-Y. Fang, , M. Quante

This study identifies KRAS mutation as a driver of invasive gastro-esophageal adenocarcinoma in a mouse model, showing its synergistic role with Tp53 or Rb1 loss and potential as a therapeutic target.

bioRxiv · May 7, 2024 · PreprintCancer Biology

Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones

A. Chandrasekaran, A. Clarke, P. G. McQueen, H.-Y. Fang, G. A. Papoian, E. Giniger

The paper uses computational simulations to show that Abl activity regulates actin network cohesiveness in axons by modulating Arp2/3 activity.

bioRxiv · Nov 1, 2021Cell Biology

Abl signaling shapes the intrinsic fluctuations of actin to direct growth of a pioneer axon in Drosophila

A. Clarke, P. McQueen, H.-Y. Fang, R. Kannan, V. Wang, E. McCreedy, S. Wincovitch, E. Giniger

This study shows Abl signaling modulates actin fluctuations in Drosophila pioneer axons to drive directed growth by promoting protrusions in leading intervals and collapsing them in lagging intervals.

bioRxiv · Jan 4, 2019Cell Biology