Author

Hanjun Cheng

Institute for Systems Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

James R. HeathiD· 2 shared Wei WeiiD· 2 shared Alphonsus H. C. NgiD· 1 shared Antoni RibasiD· 1 shared C. LiuiD· 1 shared Cameron T. FloweriD· 1 shared Charles WardeniD· 1 shared Chunmei Liu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

James R. HeathORCID

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Author profile →

2 papers

Recent·Most cited

Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer

Yapeng Su, Chunmei Liu, Xiang Lu, Hui-Yu Chuang, Guideng Li, Shiqun Shao, Yan Kong, Jihoon William Lee, Rachel H. Ng, Stephanie Wong, Lídia Robert, Charles Warden, Victoria Liu, Jie Chen, Zhuo Wang, , Wei Wei

This study identifies NF-κB-driven chromatin remodeling as a mechanism for drug-induced dedifferentiation in cancer, revealing its role in promoting drug-tolerant persister states.

Nature Communications · Apr 15, 2026Peer-reviewedCancer Biology

Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

Cameron T. Flower, C. Liu, Hui-Yu Chuang, Xiaoyang Ye, Hanjun Cheng, James R. Heath, Wei Wei, Forest M. White

The paper investigates early signaling and transcriptional changes in melanoma cells under BRAF inhibitor treatment, identifying SFK activation as a compensatory mechanism and demonstrating its sensitivity to co-inhibition.

Cell Systems · Apr 1, 2025Peer-reviewedSystems Biology