Author

Jie Chen

Nanjing Agricultural UniversityORCID 0000-0002-2916-4952Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jie Chen15 papers · Nanjing Agricultural University

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Aiwen JiangiD· 1 shared Alphonsus H. C. NgiD· 1 shared Antoni RibasiD· 1 shared Bojiang LiiD· 1 shared Caibo NingiD· 1 shared Chao DongiD· 1 shared Charles WardeniD· 1 shared Chunmei Liu· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aiwen JiangORCID

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3 papers

Recent·Most cited

Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer

Yapeng Su, Chunmei Liu, Xiang Lu, Hui-Yu Chuang, Guideng Li, Shiqun Shao, Yan Kong, Jihoon William Lee, Rachel H. Ng, Stephanie Wong, Lídia Robert, Charles Warden, Victoria Liu, Jie Chen, Zhuo Wang, , Wei Wei

This study identifies NF-κB-driven chromatin remodeling as a mechanism for drug-induced dedifferentiation in cancer, revealing its role in promoting drug-tolerant persister states.

Nature Communications · Apr 15, 2026Peer-reviewedCancer Biology

Regulation of fatty acid oxidation involved in high altitude hypoxia induced cardiomyocyte ferroptosis via the SIRT1-PPARα-GPX4 signaling pathway

Xiaona Song, Jie Chen, Hongbao Xu, Ling Zhang, Zirou Wang, Lingling Pu, Zhaoli Chen, Xinxing Wang, Weili Liu

This study identifies the SIRT1-PPARα-GPX4 pathway as a therapeutic target for high-altitude hypoxia-induced cardiac injury by regulating fatty acid oxidation and ferroptosis.

bioRxiv · Jan 20, 2025 · PreprintCell Biology

Identification of Novel Genes and Variations Associated to Glycolytic Potential Based on Pig Model

Wangjun Wu, Zengkai Zhang, Zhe Chao, Bojiang Li, Caibo Ning, Aiwen Jiang, Chao Dong, Wei Wei, Jie Chen, Honglin Liu

This study identifies novel genes and variations associated with glycolytic potential in pigs using RNA-seq and SNP analysis across different GP groups.

bioRxiv · Jul 11, 2018 · PreprintGenomics