Author

Hazel Borges

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Gaudenz M. DanuseriD· 2 shared Jinlong LiniD· 2 shared Kevin M. DeaniD· 2 shared Lizbeth Perez‐CastroiD· 2 shared Maralice Conacci‐SorrelliD· 2 shared Alecxander J Lewis· 1 shared Andrew D. WeemsiD· 1 shared Bingying Chen· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Gaudenz M. DanuserORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Modulation of Oncogenic KRAS Signaling by Branched Actin-driven Cell Membrane Protrusions

Gabriel Muhire Gihana, Kushal Bhatt, Bo-Jui Chang, Vasanth Siruvallur Murali, Felix Zhou, Jungsik Noh, Roshan Ravishankar, Hazel Borges, Jinlong Lin, Jessica Oceguera, Pedro Augusto Nogueira, Lizbeth Perez‐Castro, Niranjan Venkateswaran, Bingying Chen, Reto Paul Fiolka, , Gaudenz M. Danuser

This study shows that branched actin-driven membrane protrusions (BAMPs) enhance oncogenic KRAS signaling by amplifying upstream regulators and promoting cell proliferation through merlin inactivation.

bioRxiv · Apr 13, 2026 · PreprintCancer Biology

In vivo evidence for bleb-induced survival signaling in metastatic melanoma

Andrew D. Weems, Md Torikul Islam, Hazel Borges, Clarence Yapp, Lizbeth Perez‐Castro, Pedro Nogueira, Jinlong Lin, Zoltan Maliga, Alecxander J Lewis, Camille Kutter, Mark Mannino, Tuulia Vallius, Sandro Santagata, Peter Karl Sorger, Maralice Conacci‐Sorrell, , Gaudenz M. Danuser

This paper shows that bleb-induced septin signaling supports survival of metastatic melanoma cells in vivo, and disrupting this pathway reduces metastasis.

bioRxiv · Jan 5, 2026 · PreprintCancer Biology