Elena Chiavacci

This study examines cardiac aging in Greenland sharks, finding fibrosis, lipofuscin, and oxidative damage but no physiological decline, suggesting resilience to aging.

This study shows that rbm8a deficiency in zebrafish causes hematopoietic defects by impairing non-canonical Wnt/PCP signaling, leading to reduced thrombocytes and LPM anomalies.

The paper identifies a conserved regulatory program driving lateral plate mesoderm emergence across chordates using zebrafish and comparative analysis.

This study develops a genetic tool to spatio-temporally perturb FGF signaling in zebrafish and demonstrates its use in studying cell-autonomous requirements for FGF signaling in pectoral fin development.

This paper demonstrates efficient CRISPR-Cas9-based gene disruption in the medfly using RNPs, achieving high germline transmission and mutant phenotypes.

The paper generates two new zebrafish tbx5a frameshift alleles and compares their phenotypes to the classic hst mutant, finding differences in heart defects.

CrispRVariants provides a toolkit to accurately assess mutagenesis efficiency in genome editing experiments by analyzing sequencing data and resolving mutant alleles.