Author

Hendrik Wesseling

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Judith A. J. SteeniD· 2 shared Alicyia Walczyk MooradallyiD· 1 shared Allison M. LakeiD· 1 shared Amanda J. GuiseiD· 1 shared Andrew W. KraftiD· 1 shared Anna Blazier· 1 shared Bailin Zhang· 1 shared Biljana Djukic· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Judith A. J. SteenORCID

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Author profile →

3 papers

Recent·Most cited

CD40 ligand and IFN-γ induce proinflammatory activity and microglia-mediated neurodegeneration in human stem cell models

Timothy Hammond, Gregory S. Wirak, Sean K. Ryan, Anna Blazier, Dongyu Liu, Ivan Nyarko-Danquah, Michael LaMorte, Shameer Khader, Jose Vela, Bo Yang, Hendrik Wesseling, Bailin Zhang, Frank Rapaport, Roopali Gandhi, Biljana Djukic, Dimitry Ofengeim

This study shows CD40L and IFN-γ induce inflammation and neurodegeneration in human stem cell-derived microglia, suggesting CD40L blockade as a potential MS therapy.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Phosphorylation-dependent control of Arc protein by synaptic plasticity regulator TNIK

Alicyia Walczyk Mooradally, Jennifer Holborn, Karamjeet K. Singh, Marshall W. Tyler, Debasis Patnaik, Hendrik Wesseling, Nicholas J. Brandon, Judith A. J. Steen, Steffen P. Graether, Stephen J. Haggarty, Jasmin Lalonde

This study identifies TNIK-mediated phosphorylation sites on Arc protein, showing their role in regulating Arc's subcellular distribution and self-assembly, linking Arc and TNIK in neuronal function and psychiatric disorders.

Journal of Neurochemistry · Jun 2, 2021Peer-reviewedNeuroscience

Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brain

Darshan Sapkota, Allison M. Lake, Wei Cheng Yang, Chengran Yang, Hendrik Wesseling, Amanda J. Guise, Ceren Uncu, Jasbir Singh Dalal, Andrew W. Kraft, Jin‐Moo Lee, Mark S. Sands, Judith A. J. Steen, Joseph D. Dougherty

bioRxiv · May 16, 2018 · PreprintNeuroscience