Judith A. J. Steen

BAG2 Condensates Couple Proteostasis to CD8+T Cell Surveillance

This paper identifies I-PDBs as BAG2-driven organelles that link proteostasis to CD8+ T cell surveillance by processing pathological tau into antigenic peptides.

Phosphorylation-dependent control of Arc protein by synaptic plasticity regulator TNIK

This study identifies TNIK-mediated phosphorylation sites on Arc protein, showing their role in regulating Arc's subcellular distribution and self-assembly, linking Arc and TNIK in neuronal function and psychiatric disorders.

FLEXIQuant-LF: Robust Regression to Quantify Protein Modification Extent in Label-Free Proteomics Data

FLEXIQuant-LF quantifies protein modification extent in label-free proteomics data using robust regression, applied to APC/C mitosis data.

Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brain