Author

Heng Jui Chang

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander HostetleriD· 1 shared Amit ChoudharyiD· 1 shared Angela N. KoehleriD· 1 shared Becky S. LeiferiD· 1 shared Bocheng WuiD· 1 shared Fiona Yihan Wang· 1 shared Julia J. Zhong· 1 shared Nan JiangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexander HostetlerORCID

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1 paper

Recent·Most cited

Small molecule modulators of TOX protein re-invigorate T cell activity

Bocheng Wu, Heng Jui Chang, Prashant R. Singh, Alexander Hostetler, Yichen Xiang, Shenghao Guo, Fiona Yihan Wang, Julia J. Zhong, Becky S. Leifer, Richard P. Schiavoni, Nan Jiang, Amit Choudhary, Peter M.K. Westcott, Angela N. Koehler

This study identifies small molecule inhibitors of TOX protein that reverse T cell exhaustion and show cytotoxicity in T-ALL.

bioRxiv · Mar 3, 2025 · PreprintBiochemistry