Author

I. Glas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1

Frequent Co-Authors

S. Stertz· 7 shared A. Nenes· 5 shared A. Schaub· 5 shared B. Luo· 5 shared G. Motos· 5 shared K. Violaki· 5 shared N. Bluvshtein· 5 shared S. C. David· 5 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersMicrobiology

S. Stertz

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition

G. Motos, A. Schaub, S. C. David, L. Costa, C. C. Terrettaz, C. Kaltsonoudis, I. Glas, L. Klein, N. Bluvshtein, B. Luo, K. Violaki, M. Pohl, W. Hugentobler, U. K. Krieger, S. Pandis, , A. Nenes

This study investigates how relative humidity and aerosol composition affect influenza A virus infectivity in aerosol particles, finding that low humidity and efflorescence preserve infectivity longer than intermediate humidity conditions.

bioRxiv · May 28, 2024Microbiology

Impact of Organic Compounds on the Stability of Influenza A Virus in deposited 1-ul droplets

A. Schaub, S. C. David, I. Glas, L. K. Klein, K. Violaki, C. Terrettaz, G. Motos, N. Bluvshtein, B. Luo, M. O. Pohl, W. Hugentobler, A. Nenes, U. K. Krieger, T. Peter, S. Stertz, T. Kohn

This study examines how organic compounds affect the stability of influenza A virus in droplets, finding that proteins enhance virus stability by altering drying dynamics and efflorescence RH.

bioRxiv · May 20, 2024 · PreprintMicrobiology

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.

S. C. David, A. Schaub, C. Terrettaz, G. Motos, L. Costa, D. S. Nolan, M. Augugliaro, I. Glas, M. O. Pohl, L. K. Klein, B. Luo, N. Bluvshtein, K. Violaki, W. Hugentobler, U. K. Krieger, , T. Kohn

This study shows that respiratory commensal bacteria enhance the stability of influenza A virus in droplets and aerosols, suggesting the microbiota may influence viral transmission risks.

bioRxiv · Feb 5, 2024Microbiology

Salt supersaturation as accelerator of influenza A virus inactivation in 1-μl droplets

A. Schaub, B. Luo, S. C. David, I. Glas, L. K. Klein, L. Costa, C. Terrettaz, N. Bluvshtein, G. Motos, K. Violaki, M. Pohl, W. Hugentobler, A. Nenes, S. Stertz, U. K. Krieger, , T. Kohn

This study quantifies how salt concentration affects influenza A virus inactivation in drying droplets and explains airborne virus transmission mechanisms.

bioRxiv · Dec 21, 2023Microbiology

Inactivation mechanisms of Influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS.

S. C. David, O. Vadas, I. Glas, A. Schaub, B. Luo, G. C. D'Angelo, J. Paz Montoya, N. Bluvshtein, W. Hugentobler, L. Klein, G. Motos, M. Pohl, K. Violaki, A. Nenes, U. Krieger, , T. Kohn

This study identifies how Influenza A virus inactivates under acidic aerosol conditions using HDX-MS, revealing HA conformational changes and M1 unfolding as key mechanisms.

bioRxiv · Nov 1, 2022Microbiology

Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir

M. O. Pohl, I. Busnadiego, F. Marrafino, L. Wiedmer, A. Hunziker, S. Fernbach, I. Glas, E. V. Moroz-Omori, B. G. Hale, A. Caflisch, S. Stertz

This study combines computational screening and cellular assays to identify lenvatinib and remdesivir as synergistic inhibitors of SARS-CoV-2 replication in Vero-CCL81 cells.

bioRxiv · Mar 19, 2021Microbiology

SARS-CoV-2 Variants Reveal Features Critical for Replication in Primary Human Cells

M. O. Pohl, I. Busnadiego, V. Kufner, I. Glas, U. Karakus, S. Schmutz, M. Zaheri, I. Abela, A. Trkola, M. Huber, S. Stertz, B. G. Hale

This study identifies SARS-CoV-2 variants with distinct replication abilities in human and non-human cells, highlighting cell-specific replication features.

bioRxiv · Oct 22, 2020Microbiology