Author

I. Hurbain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 5 Organism:human· 5 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2

Frequent Co-Authors

G. Raposo· 8 shared C. Delevoye· 4 shared G. D'ANGELO· 4 shared A.-S. Mace· 3 shared C. E. Malnou· 2 shared G. Cartron· 2 shared H. Martin· 2 shared J. Izopet· 2 shared

Activity by Year

2019-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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8 shared papersCell Biology

G. Raposo

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Author profile →

8 papers

Recent·Most cited

Extracellular vesicles released by keratinocytes regulate melanosome maturation, melanocyte dendricity and pigment transfer

M.-T. Prosperi, C. Giordano, M. Gomez-duro, I. Hurbain, A.-S. Mace, G. Raposo, G. D'ANGELO

This study shows keratinocyte-derived extracellular vesicles regulate melanocyte dendrite formation, melanosome maturation, and pigment transfer, contributing to skin pigmentation and photoprotection.

bioRxiv · Dec 7, 2023Cell Biology

Human Cytomegalovirus modifies placental small extracellular vesicle secretion and composition towards a proviral phenotype to enhance infection of fetal recipient cells

M. Bergamelli, H. Martin, Y. Aubert, J.-M. Mansuy, M. Marcellin, O. Burlet-Schiltz, I. Hurbain, G. Raposo, J. Izopet, T. Fournier, A. Benchoua, M. Benard, M. Groussolles, G. Cartron, Y. Tanguy le Gac, , C. E. Malnou

This study shows hCMV infection alters placental sEVs to promote viral spread to fetal cells.

bioRxiv · Nov 18, 2021Cell Biology

PI4P and BLOC-1 remodel endosomal membranes into tubules

R. A. Jani, A. Di Cicco, T. Keren-Kaplan, S. Vale-Costa, D. Hamaoui, I. Hurbain, F.-C. Tsai, M. Dimarco, A.-S. Mace, Y. Zhu, M. J. Amorim, P. Bassereau, J. S. Bonifacino, A. Subtil, M. S. Marks, , C. Delevoye

This study shows how PI4P and BLOC-1 coordinate to form and stabilize endosomal tubules, essential for membrane remodeling and pathogen trafficking.

bioRxiv · Oct 21, 2021Cell Biology

Human cytomegalovirus infection changes the pattern of surface markers of small extracellular vesicles isolated from first trimester placental histocultures

M. Bergamelli, H. Martin, M. Benard, J. Ausseil, J.-M. Mansuy, I. Hurbain, M. Mouysset, M. Groussolles, G. Cartron, Y. Tanguy le Gac, N. Moinard, E. Suberbielle, J. Izopet, C. Tscherning, G. Raposo, , C. E. Malnou

This study examines how human cytomegalovirus infection alters surface markers on placental-derived small extracellular vesicles from first trimester histocultures.

Frontiers in Cell and Developmental Biology · Sep 10, 2021Peer-reviewedCell Biology

Catabolism of lysosome-related organelles in color-changing spiders supports intracellular turnover of pigments

F. Figon, I. Hurbain, X. Heiligenstein, S. Trepout, K. Medjoubi, A. Somogyi, C. Delevoye, G. Raposo, J. Casas

This study examines pigment organelle catabolism in crab spiders, showing they belong to the LRO family and undergo intracellular degradation without cell death or secretion.

bioRxiv · Feb 22, 2021Cell Biology

Dynlt3, a novel fundamental regulator of melanosome movement, distribution, maturation and transfer

Z. Aktary, A. Conde, F. Rambow, M. Di Marco, F. Amblard, I. Hurbain, G. Raposo, C. Delevoye, S. Coscoy, L. LARUE

This study identifies Dynlt3 as a critical regulator of melanosome transport, maturation, and transfer in melanocytes, revealing its role in skin pigmentation through interactions with the Wnt/β-catenin pathway.

bioRxiv · Jan 13, 2021 · PreprintCell Biology

Microvilli-derived Extracellular Vesicles Govern Morphogenesis in Drosophila wing epithelium

I. Hurbain, A.-S. Mace, M. Romao, L. Sengmanivong, L. Ruel, R. Basto, P. P. Therond, G. Raposo, G. D'Angelo

The paper identifies microvilli as the source of extracellular vesicles that transport Hedgehog morphogen in Drosophila wing discs, revealing the role of Prominin-like protein and cytoskeletal components in this process.

bioRxiv · Nov 1, 2020 · PreprintCell Biology

Caveolae coupling of melanocytes signaling and mechanics is required for human skin pigmentation

L. Domingues, I. Hurbain, F. Gilles-Marsens, N. Andre, M. Dewulf, M. Romao, C. Viaris de Lesegno, C. Blouin, C. Guere, K. Vie, G. Raposo, C. Lamaze, C. Delevoye

This study shows that caveolae in melanocytes couple signaling from keratinocytes to mechanical changes, essential for skin pigmentation and tissue homeostasis.

bioRxiv · Jun 10, 2019Cell Biology