Author

I. Kaymak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. M. Krawczyk· 2 shared E. H. Ma· 2 shared K. S. Williams· 2 shared L. M. DeCamp· 2 shared R. G. Jones· 2 shared S. M. Kitchen-Goosen· 2 shared A. Howden· 1 shared A. Kupai· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

C. M. Krawczyk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells

E. H. Ma, M. S. Dahabieh, L. M. DeCamp, I. Kaymak, S. M. Kitchen-Goosen, D. G. Roy, M. J. Verway, R. M. Johnson, B. Samborska, C. A. Scullion, M. Steadman, M. Vos, T. P. Roddy, C. M. Krawczyk, K. S. Williams, , R. G. Jones

This study uses 13C-labeled metabolites to show CD8+ T cells switch from glutamine to acetate metabolism during infection.

bioRxiv · Jun 9, 2023 · PreprintImmunology

Ketolysis is a metabolic driver of CD8+ T cell effector function through histone acetylation

K. M. Luda, S. M. Kitchen-Goosen, E. H. Ma, M. J. Watson, L. R. Duimstra, B. M. Oswald, J. Longo, Z. Fu, Z. Madaj, A. Kupai, B. M. Dickson, I. Kaymak, K. Lau, S. Compton, L. M. DeCamp, , R. G. Jones

This study identifies ketone bodies as essential for CD8+ T cell metabolism and effector function through histone acetylation regulation.

bioRxiv · Aug 26, 2022 · PreprintImmunology

Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses

S. Hodge, M. Krauss, I. Kaymak, J. King, A. Howden, G. Panic, R. Grencis, J. Swann, L. Sinclair, M. Hepworth

This study shows that amino acid availability regulates ILC2 responses by affecting mTOR activation and expansion, highlighting nutritional cues in innate immunity.

bioRxiv · Jun 22, 2022Immunology