Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
A. Luginina, I. Maslov, P. Khorn, O. Volkov, A. Khnykin, P. Kuzmichev, M. Shevtsov, A. Belousov, D. Dashevskii, D. Kornilov, E. Bestsennaia, J. Hofkens, J. Hendrix, T. Gensch, V. Cherezov, , V. I. Borshchevskiy
The paper compares GPCR expression in the LEXSY eukaryotic system to insect cells, finding higher protein yield in LEXSY for the A2A adenosine receptor.
Journal of Molecular Biology · Dec 1, 2023Peer-reviewedBiophysics
A. Belousov, I. Maslov, P. Orekhov, P. Khorn, P. Kuzmichev, N. Baleeva, V. Motov, A. Bogorodskiy, S. Krasnova, K. Mineev, D. Zinchenko, E. Zernii, V. Ivanovich, S. Permyakov, J. Hofkens, , V. Borshchevskiy
This study develops GFP-inspired dyes to monitor ligand-induced conformational changes in GPCRs, showing fluorescence responses to agonists and allosteric modulators.
bioRxiv · Jun 1, 2023Biophysics
Q. Coucke, N. Parveen, G. S. Fernandez, C. Qian, J. Hofkens, Z. Debyser, J. Hendrix
The paper introduces particle-based phasor-FLIM-FRET to quantify protein-protein interactions in single viral particles, showing it can accurately measure FRET efficiency with low signal intensities.
bioRxiv · May 31, 2023Biophysics
G. Wen, M. D. Lycas, Y. Jia, V. Leen, M. Sauer, J. Hofkens
The paper introduces TRITON trifunctional linkers to improve actin visualization in expansion microscopy, achieving better signal retention and anchoring.
bioRxiv · May 10, 2023Biochemistry
C. Cresens, G. Solis-Fernandez, A. Tiwari, R. Nuyts, J. Hofkens, R. Barderas, S. Rocha
The paper shows that flat clathrin lattices are more prevalent in colorectal cancer cells with higher metastatic potential.
bioRxiv · Jan 12, 2023Cancer Biology
I. Van Zundert, M. Bravo, O. Deschaume, P. Cybulski, C. Bartic, J. Hofkens, H. Uji-i, B. Fortuni, S. Rocha
This paper develops a method for antibody conjugation to nanoparticles using click chemistry, showing high targeting efficiency and reproducibility for CD44 and EGFR markers.
bioRxiv · Sep 29, 2021Biochemistry
R. Van den Eynde, W. Vandenberg, S. Hugelier, A. Bouwens, J. Hofkens, M. Müller, P. Dedecker
The paper introduces a modular structured illumination microscope (SIM) called HIT-SIM that enhances existing fluorescence microscopes with fast super-resolution imaging capabilities.
bioRxiv · Feb 25, 2021Biophysics
I. Maslov, O. Volkov, P. Khorn, P. Orekhov, A. Gusach, P. Kuzmichev, A. Gerasimov, A. Luginina, Q. Coucke, A. Bogorodskiy, V. Gordeliy, S. Wanninger, A. Barth, J. Hofkens, V. Cherezov, , V. Borshchevskiy
This study uses smFRET to analyze the conformational dynamics of the A2A adenosine receptor, revealing slow and fast dynamics in different ligand-bound states.
bioRxiv · Nov 26, 2020Biophysics
V. Gielen, V. Mönkemöller, F. Bierbuesse, A. C. Bourges, Y. Shen, J. Hofkens, P. Vanden Berghe, R. E. Campbell, B. Moeyaert, P. Dedecker
The paper introduces PEAQ biosensing, a method using photochromic single-fluorophore biosensors to measure absolute analyte concentrations or activities in live cells.
bioRxiv · Oct 29, 2020Biophysics
K. Willems, D. Ruic, F. Lucas, U. Barman, J. Hofkens, G. Maglia, P. Van Dorpe
This study develops a continuum model of the nanopore ClyA to simulate ion and water transport, revealing how ionic strength and voltage affect conductance and electro-osmotic flow.
bioRxiv · Jan 8, 2020Biophysics
G. Wen, M. Vanheusden, A. Acke, D. Vali, S. F. Mayer, R. K. Neely, V. Leen, J. Hofkens
The paper introduces a chemical linking approach for direct grafting in expansion microscopy to improve signal preservation and enable multiplexed imaging.
bioRxiv · Jul 8, 2019 · PreprintBiophysics