Author

I. Nowak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Sarshad· 2 shared C. Fernandez· 2 shared D. Angeletti· 2 shared H.-C. Huang· 2 shared J. O. Westholm· 2 shared V. Lobo· 2 shared A. A. Patel· 1 shared A. Hartlova· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

A. A. Sarshad

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response

H.-C. Huang, I. Nowak, V. Lobo, D. F. Besavilla, K. Schon, J. O. Westholm, C. Fernandez, A. A. Patel, C. Wiel, V. I. Sayin, D. G. Anastasakis, D. Angeletti, A. A. Sarshad

This study shows that influenza A virus exploits nuclear RNAi by inducing AGO2 accumulation and silencing type-I interferon genes, and that arsenic trioxide can counteract this effect.

bioRxiv · Mar 7, 2024 · PreprintBiochemistry

Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference

V. Lobo, I. Nowak, C. Fernandez, A. I. Correa Muler, J. O. Westholm, H.-C. Huang, I. Fabrik, H. T. Huynh, E. Shcherbinina, M. Poyraz, A. Hartlova, D. Benhalevy, D. Angeletti, A. A. Sarshad

This study shows that loss of Lamin A causes AGO2 to move into the nucleus, impairing RNAi and increasing oncogenic miRNA expression in cancer cells.

bioRxiv · Jun 5, 2023Biochemistry