Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
V. Lobo, I. Nowak, C. Fernandez, A. I. Correa Muler, J. O. Westholm, H.-C. Huang, I. Fabrik, H. T. Huynh, E. Shcherbinina, M. Poyraz, A. Hartlova, D. Benhalevy, D. Angeletti, A. A. Sarshad
This study shows that loss of Lamin A causes AGO2 to move into the nucleus, impairing RNAi and increasing oncogenic miRNA expression in cancer cells.
bioRxiv · Jun 5, 2023Biochemistry
N. Don-Doncow, L. Vanherle, F. Matthes, S. Kragh Petersen, H. Matuskova, S. Rattik, A. Hartlova, A. Meissner
This study shows that simvastatin reduces memory deficits linked to brain monocyte infiltration in aged ApoE-/- mice with chronic hypercholesterolemia, while BP-lowering alone has limited effects.
bioRxiv · May 15, 2020Physiology
O. Govaere, S. K. Petersen, N. Martinez-Lopez, J. Wouters, M. Van Haele, R. M. Mancina, O. Jamialahmadi, O. Bilkei-Gorzo, P. B. Lassen, R. Darlay, J. Peltier, J. M. Palmer, R. Younes, D. Tiniakos, G. P. Aithal, , A. Hartlova
This study identifies MSR1 as a key mediator of lipid-induced inflammation in NAFLD, showing its role in macrophage activation and potential as a therapeutic target.
bioRxiv · Feb 1, 2020Immunology
M. Guo, A. Hartlova, M. Gierlinski, A. Prescott, J. Castellvi, J. Hernandez Losa, S. K. Petersen, U. A. Wenzel, B. D. Dill, C. H. Emmerich, S. Ramon y Cajal, D. G. Russell, M. Trost
The paper identifies that MSR1 signaling via K63-polyubiquitylation activates JNK, promoting a pro-inflammatory switch in IL-4 activated macrophages.
bioRxiv · Feb 5, 2019Immunology
T. P. Miettinen, J. Peltier, A. Hartlova, M. Gierlinski, V. M. Jansen, M. Trost, M. Bjorklund
This study uses thermal proteome profiling to show palbociclib induces proteasome stabilization and senescence in breast cancer cells via ECM29 loss, with ECM29 mRNA levels linked to relapse-free survival.
bioRxiv · Oct 13, 2017Cancer Biology